师资队伍

生物化学与分子生物学系

马俊锋

日期:2020-08-11 点击数: 来源:


马俊锋


姓名: 马俊锋                
职称: 教授
最高学位: 博士
电话:
Email:
工作地点: 生命科学楼331室


研究方向:

1、蛋白质酪氨酸磷酸酶在疾病发生发展中的作用机制研究;2、衰老与应激的机制研究与药物筛选。

教育经历: 1996/9-2000/6,99905银河官方网,分子生物学系/99905银河官方网,生物制药,学士
2002/9-2005/6,99905银河官方网,99905银河官方网,药学/微生物与生化药学,硕士
2005/8-2008/12,美国俄克拉荷马大学,健康科学中心,联合培养博士研究生
2005/9-2009/6,99905银河官方网,99905银河官方网,药学/微生物与生化药学,博士
工作经历: 2009/7-2011/9,99905银河官方网,99905银河官方网,讲师
2011/9-2018/9,99905银河官方网,99905银河官方网,副教授
2018/9-至今,99905银河官方网,99905银河官方网,教授

研究成果:

(27)Xie W, An L, Liu Z, Wang X, Fu X, Ma J*. Therapeutic Effect of Polaprezinc on Reflux Esophagitis in the Rat Model. Dig Dis Sci. 2023 Aug;68(8):3283-3292.

(26)Yu Y, Chen J, An L, Huang T, Wang W, Cheng Z, Wang L, Xu X, Zhao Z, Fu X, Ma J*. Knockdown of phosphatases of regenerating liver-1 prolongs the lifespan of Caenorhabditis elegans via activating DAF-16/FOXO. FASEB J. 2023 Apr;37(4):e22844.

(25)An L, Fu X, Chen J, Ma J*. Application of Caenorhabditis elegans in Lipid Metabolism Research. Int J Mol Sci. 2023 Jan 7;24(2):1173.

(24)Bai S, Yu Y, An L, Wang W, Fu X, Chen J, Ma J*. Ellagic Acid Increases Stress Resistance via Insulin/IGF-1 Signaling Pathway in Caenorhabditis elegans. Molecules. 2022 Sep 20;27(19):6168.

(23)Bai S, Wang W, Zhang Z, Li M, Chen Z, Wang J, Zhao Y, An L, Wang Y, Xing S, Fu X, Ma J*. Ethanol Alleviates Amyloid-β-Induced Toxicity in an Alzheimer's Disease Model of Caenorhabiditis elegans. Front Aging Neurosci. 2021 Nov 12;13:762659.

(22)Du F, Zhou L, Jiao Y, Bai S, Wang L, Ma J*, Fu X. Ingredients in Zijuan Pu'er Tea Extract Alleviate β-Amyloid Peptide Toxicity in a Caenorhabditis elegans Model of Alzheimer's Disease Likely through DAF-16. Molecules. 2019 Feb 18;24(4):729.

(21)Zhou L, Wang L, Zhang J, Li J, Bai S, Ma J*, Fu X. Didymin improves UV irradiation resistance in C. elegans. PeerJ. 2019 Jan 9;6:e6218.

(20)Zhou L, Wang L, Bai S, Xing S, Li W, Ma J*, Fu X. Knockdown of LMW-PTP enhances stress resistance in Caenorhabditis elegans. Int J Biol Macromol. 2018; 113: 1015-1023.
(19)Zhou L, Fu X, Jiang L, Wang L, Bai S, Jiao Y, Xing S, Li W, Ma J*. Arbutin increases Caenorhabditis elegans longevity and stress resistance. PeerJ. 2017; 5: e4170.
(18)Zhou L, Fu X, Luo Y, Du F, Wang H, Xing S, Li W, Ma J*. 2-SeCD treatment extends lifespan, improves healthspan and enhances resistance to stress in Caenorhabditis elegans. RSC Adv., 2017, 7: 48245-48252
(17)Liu S, Guo Y, Wang J, Zhu H, Han Y, Jin M, Wang J, Zhou C, Ma J, Lin Q, Wang Z, Meng K, Fu X. A novel anticancer agent SNG1153 inhibits growth of lung cancer stem/progenitor cells. Oncotarget. 2016; 7(29): 45158-45170.
(16)周琳,杜方舟,李依纹,王华,陈惠鹏,付学奇,马俊锋*。耶尔森菌外膜蛋白H酪氨酸磷酸酶中药抑制剂的筛选。99905银河官方网学报(理学版),2016541):152-156
(15)Wang H, Wang K, Xiao G, Ma J, Wang B, Shen S, Fu X, Zou G, Zou B. Molecular Mechanisms for High Hydrostatic Pressure-Induced Wing Mutagenesis in Drosophila melanogaster. Sci Rep. 2015; 5: 14965.
(14)Li T, Xu X, Li J, Xing S, Zhang L, Li W, Ma J*, Fu X. Association of ACP1 gene polymorphisms and coronary artery disease in northeast Chinese population. J Genet. 2015; 94(1): 125-8.
(13)王冰莹,靳松,李依纹,马俊锋*,付学奇。以线虫为模型研究反式脂肪酸的毒理作用。吉林农业大学学报。2015371):111-114
(12)王冰莹,刘歌,周琳,付学奇,马俊锋*。以线虫为例研究复方左卡尼汀的药理及毒理作用。99905银河官方网学报(理学版)。2015531):148-152
(11)Wang B, Xu X, Cui Y, Wang H, Liu G, Zhao ZJ, Ma J*, Fu X. Caenorhabditis elegans eyes absent ortholog EYA-1 is required for stress resistance. Biochemistry (Moscow). 2014; 79(7): 653-662
(10)吴琼,王世聪,马俊锋,李婉南,邢述,付学奇。超高效液相色谱串联质谱联用法快速筛选3-羟基-3-甲基戊二酰辅酶A还原酶抑制剂。分析化学;2013417):1013-1018
(9)于笑坤,邢述,付学奇,赵志壮,马俊锋*。必需氨基酸对秀丽新杆线虫发育的影响。吉林农业大学学报。2013352):181-183
(8)马俊锋,付学奇,陈惠鹏,邢述,李婉南,康园园,尹艳春。五倍子制剂在制备鼠疫耶尔森菌外膜蛋白H抑制剂方面的应用,2013410日,ZL201110258755.8
(7)Yu X, Ma J, Lin F, Zhao W, Fu X, Zhao ZJ. Myotubularin family phosphatase ceMTM3 is required for muscle maintenance by preventing excessive autophagy in Caenorhabditis elegans. BMC Cell Biol. 2012; 13: 28.
(6)于笑坤,何潇潇,付学奇,马俊锋*。水溶性人参皂苷对秀丽隐杆线虫生物学功能的影响。99905银河官方网学报(理学版)。2012504):812-814
(5)Yu X, Zhao W, Ma J, Fu X, Zhao ZJ. Beneficial and harmful effects of alcohol exposure on Caenorhabditis elegans worms. Biochem Biophys Res Commun. 2011; 412(4): 757-62.
(4)Ma J, Li Z, Xing S, Ho WT, Fu X, Zhao ZJ. Tea contains potent inhibitors of tyrosine phosphatase PTP1B. Biochem Biophys Res Commun. 2011; 407(1): 98-102.
(3)Gao X, Lu L, Zhu M, Yuan C, Ma J, Fu X. Inhibitory Activities of Some Oxovanadium Complexes with N-Heterocyclic Ligands against PTP1B/ALP. ACTA CHIMICA SINICA, 2009; 67(9): 929-936
(2)Ma J, Zeng F, Ho W, Teng L, Li Q, Fu X, Zhao Z. Characterization and functional studies of a FYVE domain-containing phosphatase in C. elegans. J Cellular Biochem. 2008; 104(5): 1843-1852.
(1)Xing S, Ho WT, Zhao W, Ma J, Wang S, Xu X, Li Q, Fu X, Xu M, Zhao ZJ. Transgenic expression of JAK2V617F causes myeloproliferative disorders in mice. Blood; 2008; 111: 5109- 5117.